Found 263 results
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2015
Gao Y, Li Z, J Gabrielsen S, Simcox JA, Lee S-hyun, Jones D, Cooksey B, Stoddard G, Cefalu WT, McClain DA.  2015.  Adipocyte iron regulates leptin and food intake.. J Clin Invest. 125(9):3681-91.
Dow LE, O'Rourke KP, Simon J, Tschaharganeh DF, van Es JH, Clevers H, Lowe SW.  2015.  Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer.. Cell. 161(7):1539-1552.
Jones M, Chase J, Brinkmeier M, Xu J, Weinberg DN, Schira J, Friedman A, Malek S, Grembecka J, Cierpicki T et al..  2015.  Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.. J Clin Invest. 125(5):2007-20.
Korb E, Herre M, Zucker-Scharff I, Darnell RB, C Allis D.  2015.  BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice.. Nat Neurosci. 18(10):1464-73.
Dick SA, Chang NC, Dumont NA, Bell RAV, Putinski C, Kawabe Y, Litchfield DW, Rudnicki MA, Megeney LA.  2015.  Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells.. Proc Natl Acad Sci U S A. 112(38):E5246-52.
Meyer SC, Keller MD, Chiu S, Koppikar P, Guryanova OA, Rapaport F, Xu K, Manova K, Pankov D, O'Reilly RJ et al..  2015.  CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms.. Cancer Cell. 28(1):15-28.
Kim SG, Lowe EL, Dixit D, Youn CSeyeon, Kim IJ, Jung JB, Rovner R, Zack JA, Vatakis DN.  2015.  Cocaine-mediated impact on HIV infection in humanized BLT mice.. Sci Rep. 5:10010.
Hoban MD, Cost GJ, Mendel MC, Romero Z, Kaufman ML, Joglekar AV, Ho M, Lumaquin D, Gray D, Lill GR et al..  2015.  Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells.. Blood. 125(17):2597-604.
Maretzky T, Evers A, Le Gall S, Alabi RO, Speck N, Reiss K, Blobel CP.  2015.  The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding.. J Biol Chem. 290(12):7416-25.
Frieler RA, Nadimpalli S, Boland LK, Xie A, Kooistra LJ, Song J, Chung Y, Cho KW, Lumeng CN, Wang MM et al..  2015.  Depletion of macrophages in CD11b diphtheria toxin receptor mice induces brain inflammation and enhances inflammatory signaling during traumatic brain injury.. Brain Res. 1624:103-112.
Gabel HW, Kinde B, Stroud H, Gilbert CS, Harmin DA, Kastan NR, Hemberg M, Ebert DH, Greenberg ME.  2015.  Disruption of DNA-methylation-dependent long gene repression in Rett syndrome.. Nature. 522(7554):89-93.
Liu Z, Gerner MY, Van Panhuys N, Levine AG, Rudensky AY, Germain RN.  2015.  Immune homeostasis enforced by co-localized effector and regulatory T cells.. Nature. 528(7581):225-30.
Dow LE, Fisher J, O'Rourke KP, Muley A, Kastenhuber ER, Livshits G, Tschaharganeh DF, Socci ND, Lowe SW.  2015.  Inducible in vivo genome editing with CRISPR-Cas9.. Nat Biotechnol. 33(4):390-394.
Lindemans CA, Calafiore M, Mertelsmann AM, O'Connor MH, Dudakov JA, Jenq RR, Velardi E, Young LF, Smith OM, Lawrence G et al..  2015.  Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration.. Nature. 528(7583):560-564.
Kleppe M, Kwak M, Koppikar P, Riester M, Keller M, Bastian L, Hricik T, Bhagwat N, McKenney ASophia, Papalexi E et al..  2015.  JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response.. Cancer Discov. 5(3):316-31.
Soong G, Paulino F, Wachtel S, Parker D, Wickersham M, Zhang D, Brown A, Lauren C, Dowd M, West E et al..  2015.  Methicillin-resistant Staphylococcus aureus adaptation to human keratinocytes.. MBio. 6(2)
Russ JB, Borromeo MD, Kollipara RK, Bommareddy PK, Johnson JE, Kaltschmidt JA.  2015.  Misexpression of ptf1a in cortical pyramidal cells in vivo promotes an inhibitory peptidergic identity.. J Neurosci. 35(15):6028-37.
Ouyang J, Garner E, Hallet A, Nguyen HDang, Rickman KA, Gill G, Smogorzewska A, Zou L.  2015.  Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance.. Mol Cell. 57(1):108-22.
Dettmer U, Newman AJ, Soldner F, Luth ES, Kim NC, von Saucken VE, Sanderson JB, Jaenisch R, Bartels T, Selkoe D.  2015.  Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation.. Nat Commun. 6:7314.
Adam RC, Yang H, Rockowitz S, Larsen SB, Nikolova M, Oristian DS, Polak L, Kadaja M, Asare A, Zheng D et al..  2015.  Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice.. Nature. 521(7552):366-70.
Buffie CG, Bucci V, Stein RR, McKenney PT, Ling L, Gobourne A, No D, Liu H, Kinnebrew M, Viale A et al..  2015.  Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.. Nature. 517(7533):205-8.
Walsh LA, Roy DM, Reyngold M, Giri D, Snyder A, Turcan S, Badwe CR, Lyman J, Bromberg J, King TA et al..  2015.  RECK controls breast cancer metastasis by modulating a convergent, STAT3-dependent neoangiogenic switch.. Oncogene. 34(17):2189-203.
Hartlerode AJ, Morgan MJ, Wu Y, Buis J, Ferguson DO.  2015.  Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors.. Nat Struct Mol Biol. 22(9):736-43.
Jing W, Smith AA, Liu B, Li J, Hunter DJ, Dhamdhere G, Salmon B, Jiang J, Cheng D, Johnson CA et al..  2015.  Reengineering autologous bone grafts with the stem cell activator WNT3A.. Biomaterials. 47:29-40.
Comer JD, Pan FCheng, Willet SG, Haldipur P, Millen KJ, Wright CVE, Kaltschmidt JA.  2015.  Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3.. Front Neural Circuits. 9:36.