Found 51 results
Filters: Keyword is Mice, Transgenic  [Clear All Filters]
2016
Tiwari MKaushik, Adaku N, Peart N, Rogers FA.  2016.  Triplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells.. Nucleic Acids Res. 44(16):7742-54.
2015
Dow LE, O'Rourke KP, Simon J, Tschaharganeh DF, van Es JH, Clevers H, Lowe SW.  2015.  Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer.. Cell. 161(7):1539-1552.
Jones M, Chase J, Brinkmeier M, Xu J, Weinberg DN, Schira J, Friedman A, Malek S, Grembecka J, Cierpicki T et al..  2015.  Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.. J Clin Invest. 125(5):2007-20.
Frieler RA, Nadimpalli S, Boland LK, Xie A, Kooistra LJ, Song J, Chung Y, Cho KW, Lumeng CN, Wang MM et al..  2015.  Depletion of macrophages in CD11b diphtheria toxin receptor mice induces brain inflammation and enhances inflammatory signaling during traumatic brain injury.. Brain Res. 1624:103-112.
Russ JB, Borromeo MD, Kollipara RK, Bommareddy PK, Johnson JE, Kaltschmidt JA.  2015.  Misexpression of ptf1a in cortical pyramidal cells in vivo promotes an inhibitory peptidergic identity.. J Neurosci. 35(15):6028-37.
Comer JD, Pan FCheng, Willet SG, Haldipur P, Millen KJ, Wright CVE, Kaltschmidt JA.  2015.  Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3.. Front Neural Circuits. 9:36.
2014
Rongvaux A, Willinger T, Martinek J, Strowig T, Gearty SV, Teichmann LL, Saito Y, Marches F, Halene S, A Palucka K et al..  2014.  Development and function of human innate immune cells in a humanized mouse model.. Nat Biotechnol. 32(4):364-72.
Jones M, Osawa G, Regal JA, Weinberg DN, Taggart J, Kocak H, Friedman A, Ferguson DO, Keegan CE, Maillard I.  2014.  Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation.. J Clin Invest. 124(1):353-66.
Mahadevan A, Welsh IC, Sivakumar A, Gludish DW, Shilvock AR, Noden DM, Huss D, Lansford R, Kurpios NA.  2014.  The left-right Pitx2 pathway drives organ-specific arterial and lymphatic development in the intestine.. Dev Cell. 31(6):690-706.
McFadden DG, Vernon A, Santiago PM, Martinez-McFaline R, Bhutkar A, Crowley DM, McMahon M, Sadow PM, Jacks T.  2014.  p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer.. Proc Natl Acad Sci U S A. 111(16):E1600-9.
Lee L, Dale E, Staniszewski A, Zhang H, Saeed F, Sakurai M, Fa' M, Orozco I, Michelassi F, Akpan N et al..  2014.  Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease.. Sci Rep. 4:7190.
Blachere NE, Orange DE, Santomasso BD, Doerner J, Foo PK, Herre M, Fak J, Monette S, Gantman EC, Frank MO et al..  2014.  T cells targeting a neuronal paraneoplastic antigen mediate tumor rejection and trigger CNS autoimmunity with humoral activation.. Eur J Immunol. 44(11):3240-51.
2013
Diab A, Jenq RR, Rizzuto GA, Cohen AD, Huggins DW, Merghoub T, Engelhorn ME, Guevara-Patiño JA, Suh D, Hubbard-Lucey VM et al..  2013.  Enhanced responses to tumor immunization following total body irradiation are time-dependent.. PLoS One. 8(12):e82496.
Snyder EL, Watanabe H, Magendantz M, Hoersch S, Chen TA, Wang DG, Crowley D, Whittaker CA, Meyerson M, Kimura S et al..  2013.  Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.. Mol Cell. 50(2):185-99.
Lyst MJ, Ekiert R, Ebert DH, Merusi C, Nowak J, Selfridge J, Guy J, Kastan NR, Robinson ND, Alves Fde Lima et al..  2013.  Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor.. Nat Neurosci. 16(7):898-902.
2012
Griffioen KJ, Wan R, Brown TR, Okun E, Camandola S, Mughal MR, Phillips TM, Mattson MP.  2012.  Aberrant heart rate and brainstem brain-derived neurotrophic factor (BDNF) signaling in a mouse model of Huntington's disease.. Neurobiol Aging. 33(7):1481.e1-5.
DaRocha-Souto B, Coma M, Pérez-Nievas BG, Scotton TC, Siao M, Sánchez-Ferrer P, Hashimoto T, Fan Z, Hudry E, Barroeta I et al..  2012.  Activation of glycogen synthase kinase-3 beta mediates β-amyloid induced neuritic damage in Alzheimer's disease.. Neurobiol Dis. 45(1):425-37.
Argaw ATadesse, Asp L, Zhang J, Navrazhina K, Pham T, Mariani JN, Mahase S, Dutta DJ, Seto J, Kramer EG et al..  2012.  Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease.. J Clin Invest. 122(7):2454-68.
Kitchen SG, Levin BR, Bristol G, Rezek V, Kim S, Aguilera-Sandoval C, Balamurugan A, Yang OO, Zack JA.  2012.  In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells.. PLoS Pathog. 8(4):e1002649.
Chinenov Y, Gupte R, Dobrovolna J, Flammer JR, Liu B, Michelassi FE, Rogatsky I.  2012.  Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids.. Proc Natl Acad Sci U S A. 109(29):11776-81.
Vatakis DN, Bristol GC, Kim SG, Levin B, Liu W, Radu CG, Kitchen SG, Zack JA.  2012.  Using the BLT humanized mouse as a stem cell based gene therapy tumor model.. J Vis Exp. (70):e4181.
2010
Chen Y-T, Nikulina K, Lazarev S, Bahrami AF, Noble LB, Gallup M, McNamara NA.  2010.  Interleukin-1 as a phenotypic immunomodulator in keratinizing squamous metaplasia of the ocular surface in Sjögren's syndrome.. Am J Pathol. 177(3):1333-43.
Donmez G, Wang D, Cohen DE, Guarente L.  2010.  SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.. Cell. 142(2):320-32.
2009
Azim E, Shnider SJ, Cederquist GY, U Sohur S, Macklis JD.  2009.  Lmo4 and Clim1 progressively delineate cortical projection neuron subtypes during development.. Cereb Cortex. 19 Suppl 1:i62-9.
2007
Di Giorgio FPaolo, Carrasco MA, Siao MC, Maniatis T, Eggan K.  2007.  Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model.. Nat Neurosci. 10(5):608-14.