Found 50 results
Filters: Keyword is Cell Line, Tumor  [Clear All Filters]
2017
O'Rourke KP, Loizou E, Livshits G, Schatoff EM, Baslan T, Manchado E, Simon J, Romesser PB, Leach B, Han T et al..  2017.  Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer.. Nat Biotechnol. 35(6):577-582.
Röhrig F, Vorlová S, Hoffmann H, Wartenberg M, Escorcia FE, Keller S, Tenspolde M, Weigand I, Gätzner S, Manova K et al..  2017.  VEGF-ablation therapy reduces drug delivery and therapeutic response in ECM-dense tumors.. Oncogene. 36(1):1-12.
Price EW, Carnazza KE, Carlin SD, Cho A, Edwards KJ, Sevak KK, Glaser JM, de Stanchina E, Janjigian YY, Lewis JS.  2017.  Zr-DFO-AMG102 Immuno-PET to Determine Local Hepatocyte Growth Factor Protein Levels in Tumors for Enhanced Patient Selection.. J Nucl Med. 58(9):1386-1394.
2016
Guryanova OA, Shank K, Spitzer B, Luciani L, Koche RP, Garrett-Bakelman FE, Ganzel C, Durham BH, Mohanty A, Hoermann G et al..  2016.  DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.. Nat Med. 22(12):1488-1495.
Moynihan KD, Opel CF, Szeto GL, Tzeng A, Zhu EF, Engreitz JM, Williams RT, Rakhra K, Zhang MH, Rothschilds AM et al..  2016.  Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.. Nat Med. 22(12):1402-1410.
Brea EJ, Oh CY, Manchado E, Budhu S, Gejman RS, Mo G, Mondello P, Han JE, Jarvis CA, Ulmert D et al..  2016.  Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells.. Cancer Immunol Res. 4(11):936-947.
Halberg N, Sengelaub CA, Navrazhina K, Molina H, Uryu K, Tavazoie SF.  2016.  PITPNC1 Recruits RAB1B to the Golgi Network to Drive Malignant Secretion.. Cancer Cell. 29(3):339-353.
Sengelaub CA, Navrazhina K, Ross JB, Halberg N, Tavazoie SF.  2016.  PTPRN2 and PLCβ1 promote metastatic breast cancer cell migration through PI(4,5)P2-dependent actin remodeling.. EMBO J. 35(1):62-76.
Guo J, Chakraborty AA, Liu P, Gan W, Zheng X, Inuzuka H, Wang B, Zhang J, Zhang L, Yuan M et al..  2016.  pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner.. Science. 353(6302):929-32.
Lin KH, Winter PS, Xie A, Roth C, Martz CA, Stein EM, Anderson GR, Tingley JP, Wood KC.  2016.  Targeting MCL-1/BCL-XL Forestalls the Acquisition of Resistance to ABT-199 in Acute Myeloid Leukemia.. Sci Rep. 6:27696.
Behling K, Maguire WF, Puebla JCarlos Ló, Sprinkle SR, Ruggiero A, O'Donoghue J, Gutin PH, Scheinberg DA, McDevitt MR.  2016.  Vascular Targeted Radioimmunotherapy for the Treatment of Glioblastoma.. J Nucl Med. 57(10):1576-1582.
2015
Meyer SC, Keller MD, Chiu S, Koppikar P, Guryanova OA, Rapaport F, Xu K, Manova K, Pankov D, O'Reilly RJ et al..  2015.  CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms.. Cancer Cell. 28(1):15-28.
Ross JB, Huh D, Noble LB, Tavazoie SF.  2015.  Identification of molecular determinants of primary and metastatic tumour re-initiation in breast cancer.. Nat Cell Biol. 17(5):651-64.
Furlow PW, Zhang S, T Soong D, Halberg N, Goodarzi H, Mangrum C, Y Wu G, Elemento O, Tavazoie SF.  2015.  Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival.. Nat Cell Biol. 17(7):943-52.
Ouyang J, Garner E, Hallet A, Nguyen HDang, Rickman KA, Gill G, Smogorzewska A, Zou L.  2015.  Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance.. Mol Cell. 57(1):108-22.
Heilmann S, Ratnakumar K, Langdon E, Kansler E, Kim I, Campbell NR, Perry E, McMahon A, Kaufman C, van Rooijen E et al..  2015.  A Quantitative System for Studying Metastasis Using Transparent Zebrafish.. Cancer Res. 75(20):4272-4282.
Hoshino A, Costa-Silva B, Shen T-L, Rodrigues G, Hashimoto A, Mark MTesic, Molina H, Kohsaka S, Di Giannatale A, Ceder S et al..  2015.  Tumour exosome integrins determine organotropic metastasis.. Nature. 527(7578):329-35.
2014
Heath JL, Weiss JM, Lavau CP, Wechsler DS.  2014.  Effects of iron depletion on CALM-AF10 leukemias.. Exp Hematol. 42(12):1022-1030.e1.
Murphy AK, Fitzgerald M, Ro T, Kim JHyun, Rabinowitsch AI, Chowdhury D, Schildkraut CL, Borowiec JA.  2014.  Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery.. J Cell Biol. 206(4):493-507.
Dubrovsky L, Pankov D, Brea EJoseph, Dao T, Scott A, Yan S, O'Reilly RJ, Liu C, Scheinberg DA.  2014.  A TCR-mimic antibody to WT1 bypasses tyrosine kinase inhibitor resistance in human BCR-ABL+ leukemias.. Blood. 123(21):3296-304.
2013
Chiorazzi M, Rui L, Yang Y, Ceribelli M, Tishbi N, Maurer CW, Ranuncolo SM, Zhao H, Xu W, Chan W-CC et al..  2013.  Related F-box proteins control cell death in Caenorhabditis elegans and human lymphoma.. Proc Natl Acad Sci U S A. 110(10):3943-8.
2012
Pencheva N, Tran H, Buss C, Huh D, Drobnjak M, Busam K, Tavazoie SF.  2012.  Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis.. Cell. 151(5):1068-82.
Chenna V, Hu C, Pramanik D, Aftab BT, Karikari C, Campbell NR, Hong S-M, Zhao M, Rudek MA, Khan SR et al..  2012.  A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists.. Mol Cancer Ther. 11(1):165-73.
2011
Vatakis DN, Koya RC, Nixon CC, Wei L, Kim SG, Avancena P, Bristol G, Baltimore D, Kohn DB, Ribas A et al..  2011.  Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.. Proc Natl Acad Sci U S A. 108(51):E1408-16.
2009
Roberts WK, Deluca IJ, Thomas A, Fak J, Williams T, Buckley N, Dousmanis AG, Posner JB, Darnell RB.  2009.  Patients with lung cancer and paraneoplastic Hu syndrome harbor HuD-specific type 2 CD8+ T cells.. J Clin Invest. 119(7):2042-51.