Found 73 results
Filters: Keyword is Signal Transduction  [Clear All Filters]
2017
Theodosakis N, Micevic G, Langdon CG, Ventura A, Means R, Stern DF, Bosenberg MW.  2017.  p90RSK Blockade Inhibits Dual BRAF and MEK Inhibitor-Resistant Melanoma by Targeting Protein Synthesis.. J Invest Dermatol. 137(10):2187-2196.
Bhattacharya S, Yin J, Winborn CS, Zhang Q, Yue J, Chaum E.  2017.  Prominin-1 Is a Novel Regulator of Autophagy in the Human Retinal Pigment Epithelium.. Invest Ophthalmol Vis Sci. 58(4):2366-2387.
Beavers WN, Rose KL, Galligan JJ, Mitchener MM, Rouzer CA, Tallman KA, Lamberson CR, Wang X, Hill S, Ivanova PT et al..  2017.  Protein Modification by Endogenously Generated Lipid Electrophiles: Mitochondria as the Source and Target.. ACS Chem Biol. 12(8):2062-2069.
Shaffer SM, Dunagin MC, Torborg SR, Torre EA, Emert B, Krepler C, Beqiri M, Sproesser K, Brafford PA, Xiao M et al..  2017.  Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance.. Nature. 546(7658):431-435.
Peterson LW, Philip NH, DeLaney A, Wynosky-Dolfi MA, Asklof K, Gray F, Choa R, Bjanes E, Buza EL, Hu B et al..  2017.  RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense.. J Exp Med. 214(11):3171-3182.
Liang H, Zheng Q-L, Fang P, Zhang J, Zhang T, Liu W, Guo M, Robinson CL, Chen S-B, Chen X-P et al..  2017.  Targeting the PI3K/AKT pathway via GLI1 inhibition enhanced the drug sensitivity of acute myeloid leukemia cells.. Sci Rep. 7:40361.
Qi W, Gutierrez GE, Gao X, Dixon H, McDonough JA, Marini AM, Fisher AL.  2017.  The ω-3 fatty acid α-linolenic acid extends Caenorhabditis elegans lifespan via NHR-49/PPARα and oxidation to oxylipins.. Aging Cell. 16(5):1125-1135.
2016
Alabi RO, Glomski K, Haxaire C, Weskamp G, Monette S, Blobel CP.  2016.  ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds.. Circ Res. 119(4):519-31.
Wong YT, Fabiszak MM, Novikov Y, Daw ND, Pesaran B.  2016.  Coherent neuronal ensembles are rapidly recruited when making a look-reach decision.. Nat Neurosci. 19(2):327-34.
Li B, Severson E, Pignon J-C, Zhao H, Li T, Novak J, Jiang P, Shen H, Aster JC, Rodig S et al..  2016.  Comprehensive analyses of tumor immunity: implications for cancer immunotherapy.. Genome Biol. 17(1):174.
See SK, Hoogendoorn S, Chung AH, Ye F, Steinman JB, Sakata-Kato T, Miller RM, Cupido T, Zalyte R, Carter AP et al..  2016.  Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity.. ACS Chem Biol. 11(1):53-60.
Vazirani RP, Verma A, L Sadacca A, Buckman MS, Picatoste B, Beg M, Torsitano C, Bruno JH, Patel RT, Simonyte K et al..  2016.  Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance.. Diabetes. 65(6):1577-89.
Sacta MA, Chinenov Y, Rogatsky I.  2016.  Glucocorticoid Signaling: An Update from a Genomic Perspective.. Annu Rev Physiol. 78:155-80.
Carpio LR, Bradley EW, McGee-Lawrence ME, Weivoda MM, Poston DD, Dudakovic A, Xu M, Tchkonia T, Kirkland JL, van Wijnen AJ et al..  2016.  Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling.. Sci Signal. 9(440):ra79.
Kinet MJ, Malin JA, Abraham MC, Blum ES, Silverman MR, Lu Y, Shaham S.  2016.  HSF-1 activates the ubiquitin proteasome system to promote non-apoptotic developmental cell death in C. elegans.. Elife. 5
Keyes BE, Liu S, Asare A, Naik S, Levorse J, Polak L, Lu CP, Nikolova M, Pasolli HAmalia, Fuchs E.  2016.  Impaired Epidermal to Dendritic T Cell Signaling Slows Wound Repair in Aged Skin.. Cell. 167(5):1323-1338.e14.
Gee DG, Fetcho RN, Jing D, Li A, Glatt CE, Drysdale AT, Cohen AO, Dellarco DV, Yang RR, Dale AM et al..  2016.  Individual differences in frontolimbic circuitry and anxiety emerge with adolescent changes in endocannabinoid signaling across species.. Proc Natl Acad Sci U S A. 113(16):4500-5.
Peng X-P, Huang L, Liu Z-H.  2016.  miRNA-133a attenuates lipid accumulation via TR4-CD36 pathway in macrophages.. Biochimie. 127:79-85.
Zeng H, Cohen S, Guy C, Shrestha S, Neale G, Brown SA, Cloer C, Kishton RJ, Gao X, Youngblood B et al..  2016.  mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation.. Immunity. 45(3):540-554.
Kitur K, Wachtel S, Brown A, Wickersham M, Paulino F, Peñaloza HF, Soong G, Bueno S, Parker D, Prince A.  2016.  Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling.. Cell Rep. 16(8):2219-2230.
Marin EP, Jozsef L, Di Lorenzo A, Held KF, Luciano AK, Melendez J, Milstone LM, Velazquez H, Sessa WC.  2016.  The Protein Acyl Transferase ZDHHC21 Modulates α1 Adrenergic Receptor Function and Regulates Hemodynamics.. Arterioscler Thromb Vasc Biol. 36(2):370-9.
Abt MC, Buffie CG, Sušac B, Becattini S, Carter RA, Leiner I, Keith JW, Artis D, Osborne LC, Pamer EG.  2016.  TLR-7 activation enhances IL-22-mediated colonization resistance against vancomycin-resistant enterococcus.. Sci Transl Med. 8(327):327ra25.
2015
Meyer SC, Keller MD, Chiu S, Koppikar P, Guryanova OA, Rapaport F, Xu K, Manova K, Pankov D, O'Reilly RJ et al..  2015.  CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms.. Cancer Cell. 28(1):15-28.
Frieler RA, Nadimpalli S, Boland LK, Xie A, Kooistra LJ, Song J, Chung Y, Cho KW, Lumeng CN, Wang MM et al..  2015.  Depletion of macrophages in CD11b diphtheria toxin receptor mice induces brain inflammation and enhances inflammatory signaling during traumatic brain injury.. Brain Res. 1624:103-112.
Wise A, Tenezaca L, Fernandez RW, Schatoff E, Flores J, Ueda A, Zhong X, Wu C-F, Simon AF, Venkatesh T.  2015.  Drosophila mutants of the autism candidate gene neurobeachin (rugose) exhibit neuro-developmental disorders, aberrant synaptic properties, altered locomotion, and impaired adult social behavior and activity patterns.. J Neurogenet. 29(2-3):135-43.