Found 16 results
Filters: Keyword is Nuclear Proteins  [Clear All Filters]
2023
Kazansky Y, Kentsis A.  2023.  Epigenetic Cooperativity as a Therapeutic Vulnerability in Cancer.. Cancer Res. 83(23):3827-3829.
2018
Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM et al..  2018.  A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation.. Nat Cell Biol. 20(12):1410-1420.
Goyal N, Rossi MJ, Mazina OM, Chi Y, Moritz RL, Clurman BE, Mazin AV.  2018.  RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions.. Nat Commun. 9(1):34.
2017
Korb E, Herre M, Zucker-Scharff I, Gresack J, C Allis D, Darnell RB.  2017.  Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition.. Cell. 170(6):1209-1223.e20.
Spehalski E, Capper KM, Smith CJ, Morgan MJ, Dinkelmann M, Buis J, Sekiguchi JAM, Ferguson DO.  2017.  MRE11 Promotes Tumorigenesis by Facilitating Resistance to Oncogene-Induced Replication Stress.. Cancer Res. 77(19):5327-5338.
Shaffer SM, Dunagin MC, Torborg SR, Torre EA, Emert B, Krepler C, Beqiri M, Sproesser K, Brafford PA, Xiao M et al..  2017.  Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance.. Nature. 546(7658):431-435.
2016
Guryanova OA, Shank K, Spitzer B, Luciani L, Koche RP, Garrett-Bakelman FE, Ganzel C, Durham BH, Mohanty A, Hoermann G et al..  2016.  DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.. Nat Med. 22(12):1488-1495.
Falahati H, Pelham-Webb B, Blythe S, Wieschaus E.  2016.  Nucleation by rRNA Dictates the Precision of Nucleolus Assembly.. Curr Biol. 26(3):277-85.
2015
Korb E, Herre M, Zucker-Scharff I, Darnell RB, C Allis D.  2015.  BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice.. Nat Neurosci. 18(10):1464-73.
Van Laarhoven PM, Neitzel LR, Quintana AM, Geiger EA, Zackai EH, Clouthier DE, Artinger KB, Ming JE, Shaikh TH.  2015.  Kabuki syndrome genes KMT2D and KDM6A: functional analyses demonstrate critical roles in craniofacial, heart and brain development.. Hum Mol Genet. 24(15):4443-53.
2014
Karaca E, Weitzer S, Pehlivan D, Shiraishi H, Gogakos T, Hanada T, Jhangiani SN, Wiszniewski W, Withers M, Campbell IM et al..  2014.  Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function.. Cell. 157(3):636-50.
Murphy AK, Fitzgerald M, Ro T, Kim JHyun, Rabinowitsch AI, Chowdhury D, Schildkraut CL, Borowiec JA.  2014.  Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery.. J Cell Biol. 206(4):493-507.
Wong MM, Byun JS, Sacta M, Jin Q, Baek SJ, Gardner K.  2014.  Promoter-bound p300 complexes facilitate post-mitotic transmission of transcriptional memory.. PLoS One. 9(6):e99989.
2013
Snyder EL, Watanabe H, Magendantz M, Hoersch S, Chen TA, Wang DG, Crowley D, Whittaker CA, Meyerson M, Kimura S et al..  2013.  Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.. Mol Cell. 50(2):185-99.
2012
Argaw ATadesse, Asp L, Zhang J, Navrazhina K, Pham T, Mariani JN, Mahase S, Dutta DJ, Seto J, Kramer EG et al..  2012.  Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease.. J Clin Invest. 122(7):2454-68.
Wojtaszek J, Liu J, D'Souza S, Wang S, Xue Y, Walker GC, Zhou P.  2012.  Multifaceted recognition of vertebrate Rev1 by translesion polymerases ζ and κ.. J Biol Chem. 287(31):26400-8.