Noninvasive Interrogation of Cancer Metabolism with Hyperpolarized C MRI.

TitleNoninvasive Interrogation of Cancer Metabolism with Hyperpolarized C MRI.
Publication TypeJournal Article
Year of Publication2017
AuthorsCho A, Lau JYC, Geraghty BJ, Cunningham CH, Keshari KR
JournalJ Nucl Med
Volume58
Issue8
Pagination1201-1206
Date Published2017 08
ISSN1535-5667
KeywordsCarbon Isotopes, Humans, Hydrogen-Ion Concentration, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Neoplasms
Abstract

This review will highlight recent advances in hyperpolarized C MR spectroscopic imaging, which can be used to noninvasively interrogate tumor metabolism. After providing an overview of MR and hyperpolarization, we will discuss the latest advances in data acquisition techniques. Next, we will shift our focus to hyperpolarized probe design and provide an overview of the latest hyperpolarized C MR spectroscopic imaging probes developed in the last several years.

DOI10.2967/jnumed.116.182170
Alternate JournalJ. Nucl. Med.
PubMed ID28596156
Grant ListP30 CA008748 / CA / NCI NIH HHS / United States

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