Found 62 results
Filters: Keyword is Mutation  [Clear All Filters]
2023
Khodursky S, Zheng EB, Svetec N, Durkin SM, Benjamin S, Gadau A, Wu X, Zhao L.  2023.  The evolution and mutational robustness of chromatin accessibility in Drosophila.. Genome Biol. 24(1):232.
Choo Z-N, Imieliński M.  2023.  Faster detection of somatic structural variants.. Nat Biomed Eng. 7(7):847-848.
Diaz MJ, Tran JT, Choo Z-N, Root KT, Batchu S, Milanovic S, Ladehoff L, Fadil A, Lipner SR.  2023.  Genomic subtypes of cutaneous melanoma have distinct metabolic profiles: A single-cell transcriptomic analysis.. Arch Dermatol Res. 315(10):2961-2965.
Bhardwaj P, Iyengar NM, Zahid H, Carter KM, Byun DJun, Choi MHo, Sun Q, Savenkov O, Louka C, Liu C et al..  2023.  Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2.. Sci Transl Med. 15(684):eade1857.
Cortés-López M, Chamely P, Hawkins AG, Stanley RF, Swett AD, Ganesan S, Mouhieddine TH, Dai X, Kluegel L, Chen C et al..  2023.  Single-cell multi-omics defines the cell-type-specific impact of splicing aberrations in human hematopoietic clonal outgrowths.. Cell Stem Cell. 30(9):1262-1281.e8.
2022
Wang E, Mi X, Thompson MC, Montoya S, Notti RQ, Afaghani J, Durham BH, Penson A, Witkowski MT, Lu SX et al..  2022.  Mechanisms of Resistance to Noncovalent Bruton's Tyrosine Kinase Inhibitors.. N Engl J Med. 386(8):735-743.
Christophers B, Lopez MA, Gupta VA, Vogel H, Baylies M.  2022.  Pediatric Nemaline Myopathy: A Systematic Review Using Individual Patient Data.. J Child Neurol. 37(7):652-663.
Nam AS, Dusaj N, Izzo F, Murali R, Myers RM, Mouhieddine TH, Sotelo J, Benbarche S, Waarts M, Gaiti F et al..  2022.  Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.. Nat Genet. 54(10):1514-1526.
2021
Greaney AJ, Starr TN, Barnes CO, Weisblum Y, Schmidt F, Caskey M, Gaebler C, Cho A, Agudelo M, Finkin S et al..  2021.  Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies.. Nat Commun. 12(1):4196.
2018
Zhang M, Di Martino JS, Bowman RL, Campbell NR, Baksh SC, Simon-Vermot T, Kim IS, Haldeman P, Mondal C, Yong-Gonzales V et al..  2018.  Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins.. Cancer Discov. 8(8):1006-1025.
Keeffe JR, Van Rompay KKA, Olsen PC, Wang Q, Gazumyan A, Azzopardi SA, Schaefer-Babajew D, Lee YE, Stuart JB, Singapuri A et al..  2018.  A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.. Cell Rep. 25(6):1385-1394.e7.
Haque MMahfuzul, Tejero J, Bayachou M, Kenney CT, Stuehr DJ.  2018.  A cross-domain charge interaction governs the activity of NO synthase.. J Biol Chem. 293(12):4545-4554.
Zhang YM, Zimmer MA, Guardia T, Callahan SJ, Mondal C, Di Martino J, Takagi T, Fennell M, Garippa R, Campbell NR et al..  2018.  Distant Insulin Signaling Regulates Vertebrate Pigmentation through the Sheddase Bace2.. Dev Cell. 45(5):580-594.e7.
Janke AM, Seo DHee, Rahmanian V, Conicella AE, Mathews KL, Burke KA, Mittal J, Fawzi NL.  2018.  Lysines in the RNA Polymerase II C-Terminal Domain Contribute to TAF15 Fibril Recruitment.. Biochemistry. 57(17):2549-2563.
Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM et al..  2018.  A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation.. Nat Cell Biol. 20(12):1410-1420.
Lockney NA, Wang DG, Pei X, Goldman DA, Zhang Z, Lin A, Chan TA, Yamada Y, Beal K, T Yang J.  2018.  Phosphatidylinositol-3-Kinase Mutations Are Associated With Increased Local Failure in Brain Metastases Treated With Radiation.. Int J Radiat Oncol Biol Phys. 101(4):833-844.
Patel T, Bander ED, Venn RA, Powell T, Cederquist GYoung-Min, Schaefer PM, Puchi LA, Akhmerov A, Ogilvie S, Reiner AS et al..  2018.  The Role of Extent of Resection in IDH1 Wild-Type or Mutant Low-Grade Gliomas.. Neurosurgery. 82(6):808-814.
Verma N, Pan H, Doré LC, Shukla A, Li QV, Pelham-Webb B, Teijeiro V, González F, Krivtsov A, Chang C-J et al..  2018.  TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells.. Nat Genet. 50(1):83-95.
2017
Holland SM, Pierce VM, Shailam R, Glomski K, Farmer JR.  2017.  Case 28-2017. A 13-Month-Old Girl with Pneumonia and a 33-Year-Old Woman with Hip Pain.. N Engl J Med. 377(11):1077-1091.
Ptashkin RN, Pagan C, Yaeger R, Middha S, Shia J, O'Rourke KP, Berger MF, Wang L, Cimera R, Wang J et al..  2017.  Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival.. Mol Cancer Res. 15(6):708-713.
Herting CJ, Chen Z, Pitter KL, Szulzewsky F, Kaffes I, Kaluzova M, Park JC, Cimino PJ, Brennan C, Wang B et al..  2017.  Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas.. Glia. 65(12):1914-1926.
Wang W, Perens EA, Oikonomou G, Wallace SW, Lu Y, Shaham S.  2017.  IGDB-2, an Ig/FNIII protein, binds the ion channel LGC-34 and controls sensory compartment morphogenesis in C. elegans.. Dev Biol. 430(1):105-112.
Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Bozym DJ, Zhang W, Luoma A, Giobbie-Hurder A, Peter L et al..  2017.  An immunogenic personal neoantigen vaccine for patients with melanoma.. Nature. 547(7662):217-221.
Dettmer U, Ramalingam N, von Saucken VE, Kim T-E, Newman AJ, Terry-Kantor E, Nuber S, Ericsson M, Fanning S, Bartels T et al..  2017.  Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells.. Hum Mol Genet. 26(18):3466-3481.
Spehalski E, Capper KM, Smith CJ, Morgan MJ, Dinkelmann M, Buis J, Sekiguchi JAM, Ferguson DO.  2017.  MRE11 Promotes Tumorigenesis by Facilitating Resistance to Oncogene-Induced Replication Stress.. Cancer Res. 77(19):5327-5338.