Found 29 results
Filters: Keyword is Phosphorylation  [Clear All Filters]
2022
Kastan NR, Oak S, Liang R, Baxt L, Myers RW, Ginn J, Liverton N, Huggins DJ, Pichardo J, Paul M et al..  2022.  Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs.. Proc Natl Acad Sci U S A. 119(28):e2206113119.
2018
Huynh TN, Santini E, Mojica E, Fink AE, Hall BS, Fetcho RN, Grosenick L, Deisseroth K, Ledoux JE, Liston C et al..  2018.  Activation of a novel p70 S6 kinase 1-dependent intracellular cascade in the basolateral nucleus of the amygdala is required for the acquisition of extinction memory.. Mol Psychiatry. 23(6):1394-1401.
Corbit KC, Camporez JPaulo G, Edmunds LR, Tran JL, Vera NB, Erion DM, Deo RC, Perry RJ, Shulman GI, Jurczak MJ et al..  2018.  Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling.. Diabetes. 67(2):208-221.
Kazansky Y, Lai M-Y, Singh RK, Fushman D.  2018.  Impact of different ionization states of phosphorylated Serine-65 on ubiquitin structure and interactions.. Sci Rep. 8(1):2651.
Shipman WD, Chyou S, Ramanathan A, Izmirly PM, Sharma S, Pannellini T, Dasoveanu DC, Qing X, Magro CM, Granstein RD et al..  2018.  A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity.. Sci Transl Med. 10(454)
Goyal N, Rossi MJ, Mazina OM, Chi Y, Moritz RL, Clurman BE, Mazin AV.  2018.  RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions.. Nat Commun. 9(1):34.
Adam RC, Yang H, Ge Y, Lien W-H, Wang P, Zhao Y, Polak L, Levorse J, Baksh SC, Zheng D et al..  2018.  Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression.. Cell Stem Cell. 22(3):398-413.e7.
2017
Calses PC, Dhillon KK, Tucker N, Chi Y, Huang J-W, Kawasumi M, Nghiem P, Wang Y, Clurman BE, Jacquemont C et al..  2017.  DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing.. Cell Rep. 19(1):162-174.
Schardt JS, Oubaid JM, Williams SC, Howard JL, Aloimonos CM, Bookstaver ML, Lamichhane TN, Sokic S, Liyasova MS, O'Neill M et al..  2017.  Engineered Multivalency Enhances Affibody-Based HER3 Inhibition and Downregulation in Cancer Cells.. Mol Pharm. 14(4):1047-1056.
Singh RK, Kazansky Y, Wathieu D, Fushman D.  2017.  Hydrophobic Patch of Ubiquitin is Important for its Optimal Activation by Ubiquitin Activating Enzyme E1.. Anal Chem. 89(15):7852-7860.
Fu C, Xu J, Cheng W, Rojas T, Chin AC, Snowman AM, Harraz MM, Snyder SH.  2017.  Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase.. Proc Natl Acad Sci U S A. 114(8):2036-2041.
Boeynaems S, Bogaert E, Kovacs D, Konijnenberg A, Timmerman E, Volkov A, Guharoy M, De Decker M, Jaspers T, Ryan VH et al..  2017.  Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.. Mol Cell. 65(6):1044-1055.e5.
Monahan Z, Ryan VH, Janke AM, Burke KA, Rhoads SN, Zerze GH, O'Meally R, Dignon GL, Conicella AE, Zheng W et al..  2017.  Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.. EMBO J. 36(20):2951-2967.
Lv Z, Rickman KA, Yuan L, Williams K, Selvam SPanneer, Woosley AN, Howe PH, Ogretmen B, Smogorzewska A, Olsen SK.  2017.  S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.. Mol Cell. 65(4):699-714.e6.
Liang H, Zheng Q-L, Fang P, Zhang J, Zhang T, Liu W, Guo M, Robinson CL, Chen S-B, Chen X-P et al..  2017.  Targeting the PI3K/AKT pathway via GLI1 inhibition enhanced the drug sensitivity of acute myeloid leukemia cells.. Sci Rep. 7:40361.
2016
Jung C, Rabinowitsch A, Lee WTing, Zheng D, de Vaca SCabeza, Carr KD.  2016.  Effects of food restriction on expression of place conditioning and biochemical correlates in rat nucleus accumbens.. Psychopharmacology (Berl). 233(17):3161-72.
Guo J, Chakraborty AA, Liu P, Gan W, Zheng X, Inuzuka H, Wang B, Zhang J, Zhang L, Yuan M et al..  2016.  pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner.. Science. 353(6302):929-32.
Tiwari MKaushik, Adaku N, Peart N, Rogers FA.  2016.  Triplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells.. Nucleic Acids Res. 44(16):7742-54.
2015
Dick SA, Chang NC, Dumont NA, Bell RAV, Putinski C, Kawabe Y, Litchfield DW, Rudnicki MA, Megeney LA.  2015.  Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells.. Proc Natl Acad Sci U S A. 112(38):E5246-52.
Peng X-X, Lister A, Rabinowitsch A, Kolaric R, S de Vaca C, Ziff EB, Carr KD.  2015.  Episodic sucrose intake during food restriction increases synaptic abundance of AMPA receptors in nucleus accumbens and augments intake of sucrose following restoration of ad libitum feeding.. Neuroscience. 295:58-71.
Lindemans CA, Calafiore M, Mertelsmann AM, O'Connor MH, Dudakov JA, Jenq RR, Velardi E, Young LF, Smith OM, Lawrence G et al..  2015.  Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration.. Nature. 528(7583):560-564.
Hoshino A, Costa-Silva B, Shen T-L, Rodrigues G, Hashimoto A, Mark MTesic, Molina H, Kohsaka S, Di Giannatale A, Ceder S et al..  2015.  Tumour exosome integrins determine organotropic metastasis.. Nature. 527(7578):329-35.
2014
Murphy AK, Fitzgerald M, Ro T, Kim JHyun, Rabinowitsch AI, Chowdhury D, Schildkraut CL, Borowiec JA.  2014.  Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery.. J Cell Biol. 206(4):493-507.
Kim H-J, Raphael AR, LaDow ES, McGurk L, Weber RA, Trojanowski JQ, Lee VM-Y, Finkbeiner S, Gitler AD, Bonini NM.  2014.  Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models.. Nat Genet. 46(2):152-60.
2013
Ebert DH, Gabel HW, Robinson ND, Kastan NR, Hu LS, Cohen S, Navarro AJ, Lyst MJ, Ekiert R, Bird AP et al..  2013.  Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR.. Nature. 499(7458):341-5.