Title | Crystal methamphetamine use and HIV medical outcomes among HIV-infected men who have sex with men accessing support services in New York. |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Feldman MB, Thomas JA, Alexy ER, Irvine MK |
Journal | Drug Alcohol Depend |
Volume | 147 |
Pagination | 266-71 |
Date Published | 2015 Feb 01 |
ISSN | 1879-0046 |
Keywords | Amphetamine-Related Disorders, CD4 Lymphocyte Count, Female, HIV Infections, Homosexuality, Male, Humans, Male, New York City, Viral Load |
Abstract | BACKGROUND: Drug use poses multiple challenges to maintaining physical health among HIV-infected individuals, particularly with regard to disease progression. Few studies, however, have examined the association between the use of crystal methamphetamine ("crystal meth") and HIV disease progression specifically among HIV-infected men who have sex with men (MSM). Understanding this relationship among HIV-infected MSM is particularly critical because of the high rates of crystal meth use reported in the population. METHODS: Associations between recent crystal meth use and poor HIV medical outcomes (viral load>200 copies/mL, CD4 count <350 cells/mm(3)) were analyzed for 2896 HIV-infected MSM enrolled in Ryan White Part A programs in the greater New York metropolitan area between November 2010 and June 2012. RESULTS: Crystal meth use (reported by 4%) was independently associated with unsuppressed viral load (AOR=1.8, CI=1.1-2.9) in multivariate analyses controlling for sociodemographic characteristics. There was no significant relationship between crystal meth use and low CD4 counts. CONCLUSIONS: To date, little research has examined how crystal meth use influences HIV medical outcomes among HIV-infected MSM. This analysis showed a significant independent association between crystal meth use and unsuppressed viral load among MSM in an HIV service population. Future studies should examine biological and psychosocial mediators, moderators and confounders of this relationship to inform intervention development for MSM crystal meth users in HIV care settings. |
DOI | 10.1016/j.drugalcdep.2014.09.780 |
Alternate Journal | Drug Alcohol Depend |
PubMed ID | 25482501 |
Grant List | H89HA00015 / / PHS HHS / United States |
Submitted by kej2006 on June 6, 2018 - 4:11pm