Title | Eudesmane-Type Sesquiterpene Glycosides from Dictamnus dasycarpus Turcz. |
Publication Type | Journal Article |
Year of Publication | 2018 |
Authors | Yang S, Li Z, Wang J, Ruan J, Zheng C, Huang P, Han L, Zhang Y, Wang T |
Journal | Molecules |
Volume | 23 |
Issue | 3 |
Date Published | 2018 Mar 13 |
ISSN | 1420-3049 |
Abstract | Eudesmane-type sesquiterpenes have been reported to exhibit varieties of biological activities. During the process of investigating this kind of natural product from the root bark of Turcz., 13 eudesmane-type sesquiterpene glycosides including six new isolates, named as dictameudesmnosides A₁ (), A₂ (), B (), C (), D (), and E (), together with seven known ones (-), were obtained. Herein, their structures were determined by the analysis of physical data, spectroscopic analysis, and chemical methods. The existence of α-configuration glucose units in their structures (-, ) is not very common in natural glycosidic components. Meanwhile, compounds -, , and - displayed TG accumulation inhibitory effects on HepG2 cells. |
DOI | 10.3390/molecules23030642 |
Alternate Journal | Molecules |
PubMed ID | 29533968 |
Submitted by kej2006 on June 6, 2018 - 4:13pm