Submitted by api_import on June 6, 2018 - 4:09pm
Title | Metabolic control of asyMYCtric division. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Do MH, Li MO |
Journal | Cell Res |
Volume | 26 |
Issue | 8 |
Pagination | 863-4 |
Date Published | 2016 08 |
ISSN | 1748-7838 |
Keywords | CD8-Positive T-Lymphocytes, Cell Division, Lymphocyte Count |
Abstract | Asymmetric division in CD8 T cells produces two daughter cells expressing different levels of c-Myc with distinct metabolic profiles. Manipulating this asymmetric partitioning of c-Myc skews T cell responses and potentially allows the development of more effective vaccines and cancer immunotherapies. |
DOI | 10.1038/cr.2016.60 |
Alternate Journal | Cell Res. |
PubMed ID | 27197568 |
PubMed Central ID | PMC4973327 |
Grant List | P30 CA008748 / CA / NCI NIH HHS / United States |