Submitted by bel2021 on October 23, 2020 - 3:22pm
| Title | Secukinumab Lowers Expression of ACE2 in Affected Skin of Patients With Psoriasis. |
| Publication Type | Journal Article |
| Year of Publication | 2020 |
| Authors | Krueger JG, Murrell DF, Garcet S, Navrazhina K, Lee PC, Muscianisi E, Blauvelt A |
| Journal | J Allergy Clin Immunol |
| Date Published | 2020 Sep 28 |
| ISSN | 1097-6825 |
| Abstract | Capsule summary (33 of 35 words; 2 of 2 sentences): Secukinumab reduced the inflammation and the expression of ACE2, which encodes the SARS-CoV-2 receptor, in plaques of patients with psoriasis. Reductions in ACE2 expression with secukinumab significantly correlated with reductions in disease activity. |
| DOI | 10.1016/j.jaci.2020.09.021 |
| Alternate Journal | J Allergy Clin Immunol |
| PubMed ID | 33002515 |