Found 7 results
Filters: Keyword is Structure-Activity Relationship  [Clear All Filters]
2018
Kazansky Y, Lai M-Y, Singh RK, Fushman D.  2018.  Impact of different ionization states of phosphorylated Serine-65 on ubiquitin structure and interactions.. Sci Rep. 8(1):2651.
2017
Lv Z, Rickman KA, Yuan L, Williams K, Selvam SPanneer, Woosley AN, Howe PH, Ogretmen B, Smogorzewska A, Olsen SK.  2017.  S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.. Mol Cell. 65(4):699-714.e6.
2016
Konkle ME, Blobaum AL, Moth CW, Prusakiewicz JJ, Xu S, Ghebreselasie K, Akingbade D, Jacobs AT, Rouzer CA, Lybrand TP et al..  2016.  Conservative Secondary Shell Substitution In Cyclooxygenase-2 Reduces Inhibition by Indomethacin Amides and Esters via Altered Enzyme Dynamics.. Biochemistry. 55(2):348-59.
See SK, Hoogendoorn S, Chung AH, Ye F, Steinman JB, Sakata-Kato T, Miller RM, Cupido T, Zalyte R, Carter AP et al..  2016.  Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity.. ACS Chem Biol. 11(1):53-60.
2015
Dettmer U, Newman AJ, von Saucken VE, Bartels T, Selkoe D.  2015.  KTKEGV repeat motifs are key mediators of normal α-synuclein tetramerization: Their mutation causes excess monomers and neurotoxicity.. Proc Natl Acad Sci U S A. 112(31):9596-601.
2004
Peterson JR, Bickford LC, Morgan D, Kim AS, Ouerfelli O, Kirschner MW, Rosen MK.  2004.  Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.. Nat Struct Mol Biol. 11(8):747-55.
2002
Eakin CM, Knight JD, Morgan CJ, Gelfand MA, Miranker AD.  2002.  Formation of a copper specific binding site in non-native states of beta-2-microglobulin.. Biochemistry. 41(34):10646-56.